DR. GEORGE SCHEELE

 CURRICULUM VITAE

 INVENTIONS

 PATENTS

 COMPANY FOUNDER

 PH Pharmaceuticals Inc.
 Viral Shield
  Pharmaceuticals Inc.
 NovaLife Inc.
 La Jolla Biosciences LLC
 Alpha Gene Inc.

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 ORGANIZATIONS

 CONTACT DR. SCHEELE

 

 


As my several careers unfolded I have been fascinated by the power of the written word, phrase or text in communicating current information and new ideas in strong, powerful ways. These interests have resulted in a professional lifetime dedicated to publishing books (3), book chapters (26), original scientific papers (84) and patent applications (7).

BOOKS:

Illustration of the two editions of "The Pancreas"

•  Organized and co-edited the first edition of the leading resource book in the field, entitled "The Pancreas, Biology, Pathobiology and Diseases" (V.L. Go, J.D. Gardner, F.P. Brooks , E. Lebenthal, E.P. DiMagno, G.A. Scheele, eds.) Raven Press, New York , NY., 1986; first edition, 1986. Five chapters in this book were written by Dr. Scheele:

Regulation of Gene Expression in the Exocrine Pancreas. George A. Scheele

Cellular processing of Proteins in the exocrine Pancreas. George A. Scheele

Two-Dimensional Gel Electrophoresis in the Analysis of Exocrine Pancreatic Proteins. George A. Scheele.

Effects of Nutrition on the Exocrine Pancreas. C.S. Pitchumoni, G. Scheele, P.C. Lee and E. Lebenthal.

Experimental Models and Concepts in Acute Pancreatitis. Guido Adler, horst F. Kern and George A. Scheele.

•  Organized and co-edited the second edition of the leading textbook in the field, entitled "The Pancreas, Biology, Pathobiology and Diseases" (V.L. Go, E.P. DiMagno, J.D. Gardiner, E. Lebenthal , H.A. Reber and G.A. Scheele, eds.) Raven Press, New York , NY., second edition, 1993. Four chapters in this book were written by Dr. Scheele:

Regulation of pancreatic Gene Expression in Response to Hormones and Nutritional Substrates. George A. Scheele

Cellular Compartmentation, protein Processing and secretion in the Exocrine Pancreas. George A. Scheele and Horst F. Kern.

The Use of Two-dimensional Gel Electrophoresis and High-Performance Liquid chromatography for the Analysis of Pancreatic Juice. P. J. Padfield and George A. Scheele.

Interdependence of Nutrition and Exocrine Pancreatic Function. C.S. Pitchumoni and George A. Scheele.

The Obesity Cure:

Dr. Scheele's newest book, The Obesity Cure, explains how Power Amino Acids® correct for deficiencies in positive-charged amino acids and proteins, that lead to metabolic imbalances associated with chronic degenerative disease and the Metabolic Syndrome. The book will be available on all commercial E-book websites in May, 2011. The following is a short description of the book:

At last, a breakthrough in nutritional science that identifies both the cause and solution of obesity, America's #1 metabolic disease.

Using a lifetime of scientific achievement and clinical insight, Nobel associate and author, Dr. George Scheele, explains how to use nature's gift--Power Amino Acids®--to avoid "addictive taste disorders" and harness the body's own feedback mechanisms to tame appetite, rebalance metabolism, and normalize body weight.

In The Obesity Cure Dr. Scheele shows that obesity is only one in a spectrum of metabolic diseases associated with the Metabolic Syndrome and accelerated aging. He demonstrates how the current "paradoxes" of obesity and metabolic health prove that something "essential" is missing in our current understanding of nutritional health and weight control.

The Obesity Cure identifies the missing "piece" as Power Amino Acids®. These essential ingredients have the ability to correct deficiencies in the food chain, including positive-charged amino acids, proteins, and metabolic pathways that adversely affect satiety, metabolic health, and body weight.

Without Power Amino Acids®, the body suffers from "protein deficiency syndrome," a newly identified condition that limits the body's ability to regulate the satiety centers and metabolic pathways that control weight gain and loss.

The Obesity Cure reveals the breakthrough importance of supplementing the diet with essential, positive-charged, and satiety-producing amino acids ("Power Amino Acids") that tame appetite and rebalance the metabolic pathways to burn fat and maintain normal body weight with the satiety feelings of comfort, satisfaction, and well-being.

LAY ARTICLES:

HUMAN CONNECTIONS: DEAR TO THE HEART

In response to the 9/11 attack on the trade towers in NY City in 2001, Dr. Scheele provided a poignant commentary on both the attack and the state of the American culture at the beginning of the 3rd millennium.

PDF FILE: Human Connections: Dear to the Heart

CHAPTERS:

•  Scheele, G.A. (1976) Secretory proteins of the exocrine pancreas. In Cell Biology (PL Altman and DD Katz, eds., Federation of American Societies for Experimental Biology, Bethesda , MD , pp 334-6.

•  Scheele, G. (1980) Biosynthesis, segregation, and secretion of exportable proteins in the exocrine pancreas. Am. J. Physiol. 1: G467-77.

•  Scheele, G. (1981) Analysis of the secretory process in the exocrine pancreas by two-dimensional isoelectric focusing/sodium dodecyl sulfate gel electrophoresis. In Methods in Cell Biology (A. Hand and C. Oliver, eds.), 23: 345-58.

•  Scheele, G. (1982) Pancreatic zymogen granules, In The Secretory Granule (A. Poisner and J. Trifaro, eds.) Elsevier Biomedical Press, pp 213-46.

•  Carne, T. and Scheele, G. (1983) The role of presecretory proteins in the secretory process. In The Secretory Process (ed. Marc Cantin) Karger Press, Basel , Switzerland , pp 73-101.

•  Scheele, G. (1983) Methods for the study of protein translocation across the RER membrane using the reticulocyte lysate translation system and canine pancreatic microsomal membranes. In Methods in Enzymology, Biomembranes (eds. S. Fleicher and B. Fleicher) 96: 94-110.

•  Scheele, G. (1983) pancreatic Lobules in the in vitro study of pancreatic acinar cell function, In Methods in Enzymology, Biomembranes (eds. S. Fleicher and B. Fleicher), 98: 17-27.

•  Kern, H., Adler, G. and Scheele, G. (1984) Concept of flow and compartmentation in understanding the pathobiology of pancreatitis. In Pancreatitis, Concepts and Classification (eds. Gyr, K., Singer, M. and Sarles, H.) Elsevier Biomedical Press, pp 3-9.

•  Scheele, G., Adler, G. and Kern, H. (1984) The role of lysosomes in the development of acute pancreatitis, In Pancreatitis, Concepts and Classification (eds. K. Gyr, M. Singer and H. Sarles) Elsevier Biomedical Press, pp 17-23.

•  Scheele, G. (1984) Analysis of human exocrine proteins in health and disease by use of two dimensional isoelectric focusing/SDS gel electrophoresis. In Pancreatitis, Concepts, and Classification (eds. K. Gyr, M. Singer, and H. Sarles) Elsevier Biomedical Press, pp 89-94

•  Scheele, G. (1984) Biochemical concepts and markers in pancreatitis, In Pancreatitis, Concepts and Classification (eds. K. Gyr, M. Singer and H. Sarles) Elsevier Biomedical Press, pp119-125.

•  Scheele, G. (1986) Early biochemical events in the biogenesis and topogenesis of secretory and membrane proteins, In Molecular and Cellular Biology of Digestion (P. Desnuelle, H. Sjostrom, and O. Noren, eds.) Elsevier Biomedical Press, pp 43-59.

•  Scheele, G. and Kern, H. (1986) The exocrine pancreas, In Molecular Cellular Biology of Digestion (P. Desnuelle, H. Sjostrom, and O. Noren, eds.) Elsevier Biomedical Press, pp 173-194.

•  Adler, G., Kern, H. and Scheele, G. (1986) Experimental models and concepts in acute pancreatitis, In The Exocrine Pancreas: Biology, Pathobiology and Diseases (V.L. Go, J.D. Gardner, F.P., Brooks, E. Lebenthal, E.P. DiMagno, G.A. Scheele, eds.) Raven Press. New York , NY , pp 407-421.

•  Scheele, G. (1986) Two dimensional electrophoresis in the analysis of exocrine pancreatic proteins, In The Exocrine Pancreas: Biology, Pathobiology and Diseases (V.L. Go, J.D. Gardner, F.P., Brooks, E. Lebenthal, E.P. DiMagno, G.A. Scheele, eds.) Raven Press. New York , NY , pp 185-192.

•  Scheele, G. (1986) Cellular processing of proteins in the exocrine pancreas, In The Exocrine Pancreas: Biology, Pathobiology and Diseases (V.L. Go, J.D. Gardner, F.P., Brooks, E. Lebenthal, E.P. DiMagno, G.A. Scheele, eds.) Raven Press. New York , NY , pp 69-85.

•  Scheele, G. (1986) Regulation of gene expression in the exocrine pancreas, In The Exocrine Pancreas: Biology, Pathobiology and Diseases (V.L. Go, J.D. Gardner, F.P., Brooks, E. Lebenthal, E.P. DiMagno, G.A. Scheele, eds.) Raven Press. New York , NY , pp 55-67.

•  Ptichumoni, C.S., Scheele, G.A., Lee, P.C., Lebenthal, E. (1986) Effects of nutrition on the exocrine pancreas, In The Exocrine Pancreas: Biology, Pathobiology and Diseases (V.L. Go, J.D. Gardner, F.P., Brooks, E. Lebenthal, E.P. DiMagno, G.A. Scheele, eds.) Raven Press. New York , NY , pp 387-406.

•  Kern, H., Rausch, U. and Scheele, G. (1986) Pancreatic adaptation to nutritional substrates in the diet is regulated by specific hormones, In Adaptation in the Small Instestine and Pancreas (H. Dowling, U. Folsch and E.O. Riecken, eds.) Gut, 28: 89-94.

•  Scheele, G. and Kern, H.F. (1989) Cellular compartmentation and protein processing in the exocrine pancreas. Handbook Physiol., Section 6, The Gastrointestinal System, Vol. III, salivary, gastric, pancreatic and hepatobiliary secretion (J. Forte, ed.) Oxford University Press, NY, pp 477-498.

•  Scheele, G. and Kern H.F. (1989) Selective regulation of gene expression in the exocrine pancreas. Handbook Physiol., Section 6, The Gastrointestinal System, Vol. III, salivary, gastric, pancreatic and hepatobiliary secretion (J. Forte, ed.) Oxford University Press, NY, pp 499-513.

•  Padfield, P.J. and Scheele, G.A. (1993) The use of two-dimensional gel electrophoresis and high performance liquid chromatography for the analysis of pancreatic juice, In The Pancreas, Biology, Pathobiology and Diseases (V.L. Go, J.D. Gardiner, H.A. Reber, E. Lebenthal, E.P. DiMagno, G.A. Scheele, eds.) Raven Press, New York , NY pp 265-273.

•  Ptichumoni, C.S. and Scheele, G.A. (1993) Interdependence of nutrition and exocrine pancreatic function, In The Pancreas, Biology, Pathobiology and Diseases (V.L. Go, J.D. Gardiner, H.A. Reber, E. Lebenthal, E.P. DiMagno, G.A. Scheele, eds.) Raven Press, New York , NY pp 449-473.

•  Scheele, G. (1993) Regulation of pancreatic gene expression in response to hormones and nutritional substrates, In The Pancreas, Biology, Pathobiology and Diseases (V.L. Go, J.D. Gardiner, H.A. Reber, E. Lebenthal, E.P. DiMagno, G.A. Scheele, eds.) Raven Press, New York , NY pp 103-120.

•  Scheele, G.A. and Kern, H.F. (1993) Cellular compartmentation, protein processing and secretion in the exocrine pancreas, In The Pancreas, Biology, Pathobiology and Diseases (V.L. Go, J.D. Gardiner, H.A. Reber, E. Lebenthal, E.P. DiMagno, G.A. Scheele, eds.) Raven Press, New York , NY pp 121-150.

•  Scheele, G.A. (1993) Extracellular and intracellular messengers in diet-induced regulation of pancreatic gene expression, In Physiology of the Gastrointestinal Tract (L.R. Johnson, ed.) Raven Press, New York , NY ,

SCIENTIFIC PAPERS:

See Bibliography

PATENTS:

See Inventor

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